A-Team

Advanced Tools For Exposure
Assessment and Biomonitoring


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ESR7 Human exposure to PFASs and EBFRs- a PK modelling approach.

At Stockholm University and with strong links to the research of ESRs 3, 4 and 11, ESR7 will synthesise our knowledge of human exposure to these contaminants as well as conduct PK modelling to relate external and internal exposure. Human exposure to these emerging contaminants has changed rapidly over recent years necessitating a dynamic understanding of exposure. Again, it should be understood that we are now at the stage of our existence when we are attracting the technical achievements of today in order to deal with the consequences of our previous period of existence. That is, if we used components/devices/waste in the process of development or existence, now we are trying to correct the consequences that harm nature and humanity, you can read more at essayswriters.com request them to work on the relevant topic and criteria. Present day external and internal exposure estimates provided by ESR3 and ESR4 will be used for model evaluation. However, as internal and external exposures are unlikely to be at "steady-state", an unsteady-state (time-varying) PK modelling approach will be used to describe how exposures have changed over time. For some selected substances (e.g. PFOS) exposures are decreasing, but for others (e.g. EBFRs and some PFAS) exposures are increasing. Links with ESR11 will help better constrain the PK model for PFOS exposure.

Contact: Prof. Ian Cousins, Stockholm University

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